@Aaron210419 Forgot to mention as an aside the sex drive matter...
Women are really prone to flucutations in hormones especially as we get into the peri-menopause years. That can start in a woman's mid thirties for most and marches it's way until you hit full menopause which can start in late 40s/early 50s. Instead of arguing about her sex drive do something about it if she is open to the idea. Many doctors now will prescribe compounded bioidentical hormones (BHRT) to help balance those things out. For sex drive issues they will give her testosterone cream that works very quickly to put her in the mood. Testosterone also help lessen some symptoms of depression.
Biodentical Hormone therapy is not the same thing as prescription based Hormone Replacement therapy (HRT). Premarin which is what they use for estrogen and Provera which is what is used for progesterone have dangerous side effects and can cause cancer in 1 out 100,000 women and can lead to weight gain. They are synthetic drugs. IMO steer clear of these "drugs."
You don't say what your ages are but if your wife is already close to menopause she could be suffering from a lack of estrogen. Losing our estrogen can make sex extremely painful. The pain leads to a psychological aversion to having sex which further compounds the issues. "Things" shrink and atrophy causing the tissue in that region to thin out without estrogen. Again a doctor can help with this with estrogen suppositories or cream, pellet therapy (injected into the hip), and many other solutions. There are also over the counter suppositories that lube things up and give that region a teensey bit of estrogen (like 1% of Estrione or Estrial). There is even a procedure that uses a C02 laser that can restore that part of a woman's anatomy to it's former glory. That procedure is called The Mona Lisa Touch and it is generally not covered by insurance. It will set you back around $3000. Pain during intercourse is a silent epidemic and many woman won't discuss it with anyone - intimate partner or doctor alike. Ask your wife how sex feels for her. Try and use observation to determine if she is experiencing discomfort. For example does she try and push you away or clamp her legs up or something like that?
BTW men also start experiencing a decline in testosterone as they age. A doctor can provide a similar type of therapy in the form of bioidentical testosterone injected as a pellet. We are in a glorious age people where we don't have to suffer and our relationships don't either. Use these tools to make things better!
Disclaimer: I'm not a doctor so please consult one to get the whole story